Ribonuclease H activities associated with viral reverse transcriptases are endonucleases.
A series of test substrates have been synthesized to establish the effect of termini on the putative exoribonuclease H activity of reverse transcriptase. Recombinant reverse transcriptase from human immunodeficiency virus, natural enzyme from avian myeloblastosis virus, and a known endonuclease, Esc...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1989
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287173/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2471188/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.10.3539 |
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