Targeting HIV-1 RNase H: <i>N’</i>-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants

HIV-1 infection requires life-long treatment and with 2.1 million new infections/year, faces the challenge of an increased rate of transmitted drug-resistant mutations. Therefore, a constant and timely effort is needed to identify new HIV-1 inhibitors active against drug-resistant variants. The ribo...

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Detaylı Bibliyografya
Asıl Yazarlar:	Angela Corona, Ester Ballana, Simona Distinto, Dominga Rogolino, Claudia Del Vecchio, Mauro Carcelli, Roger Badia, Eva Riveira-Muñoz, Francesca Esposito, Cristina Parolin, José A. Esté, Nicole Grandi, Enzo Tramontano
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	MDPI AG 2020-07-01
Seri Bilgileri:	Viruses
Konular:	HIV-1 antivirals ribonuclease H RNase H <i>N</i>-acylhydrazone RT
Online Erişim:	https://www.mdpi.com/1999-4915/12/7/729
Etiketler:	Etiketle Etiket eklenmemiş, İlk siz ekleyin!

Targeting HIV-1 RNase H: <i>N’</i>-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants

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