Targeting HIV-1 RNase H: <i>N’</i>-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants

HIV-1 infection requires life-long treatment and with 2.1 million new infections/year, faces the challenge of an increased rate of transmitted drug-resistant mutations. Therefore, a constant and timely effort is needed to identify new HIV-1 inhibitors active against drug-resistant variants. The ribo...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Angela Corona, Ester Ballana, Simona Distinto, Dominga Rogolino, Claudia Del Vecchio, Mauro Carcelli, Roger Badia, Eva Riveira-Muñoz, Francesca Esposito, Cristina Parolin, José A. Esté, Nicole Grandi, Enzo Tramontano
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2020-07-01
Serie:	Viruses
Soggetti:	HIV-1 antivirals ribonuclease H RNase H <i>N</i>-acylhydrazone RT
Accesso online:	https://www.mdpi.com/1999-4915/12/7/729
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!