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Improved gene expression upon transfer of the adenosine deaminase minigene outside the transcriptional unit of a retroviral vector.

This study describes a type of retroviral vector called double-copy (DC) vector that was designed to improve the expression of transduced genes. The unique feature of DC vectors is that the transduced gene is inserted within the U3 region of the 3' long terminal repeat (LTR). Consequently, in t...

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Detalhes bibliográficos
Main Authors: Hantzopoulos, P A, Sullenger, B A, Ungers, G, Gilboa, E
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC287169/
https://ncbi.nlm.nih.gov/pubmed/2542934
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