Glycosylation Pattern of Mature Dimeric Leukocyte and Recombinant Monomeric Myeloperoxidase: GLYCOSYLATION IS REQUIRED FOR OPTIMAL ENZYMATIC ACTIVITY

The involvement of myeloperoxidase (MPO) in various inflammatory conditions has been the scope of many recent studies. Besides its well studied catalytic activity, the role of its overall structure and glycosylation pattern in biological function is barely known. Here, the N-glycan composition of na...

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Autores principales: Van Antwerpen, Pierre, Slomianny, Marie-Christine, Boudjeltia, Karim Zouaoui, Delporte, Cedric, Faid, Valegh, Calay, Damien, Rousseau, Alexandre, Moguilevsky, Nicole, Raes, Martine, Vanhamme, Luc, Furtmüller, Paul G., Obinger, Christian, Vanhaeverbeek, Michel, Nève, Jean, Michalski, Jean-Claude
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Glycobiology and Extracellular Matrices
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871502/
https://ncbi.nlm.nih.gov/pubmed/20332087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.089748
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