Glycosylation Pattern of Mature Dimeric Leukocyte and Recombinant Monomeric Myeloperoxidase: GLYCOSYLATION IS REQUIRED FOR OPTIMAL ENZYMATIC ACTIVITY

The involvement of myeloperoxidase (MPO) in various inflammatory conditions has been the scope of many recent studies. Besides its well studied catalytic activity, the role of its overall structure and glycosylation pattern in biological function is barely known. Here, the N-glycan composition of na...

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Main Authors: Van Antwerpen, Pierre, Slomianny, Marie-Christine, Boudjeltia, Karim Zouaoui, Delporte, Cedric, Faid, Valegh, Calay, Damien, Rousseau, Alexandre, Moguilevsky, Nicole, Raes, Martine, Vanhamme, Luc, Furtmüller, Paul G., Obinger, Christian, Vanhaeverbeek, Michel, Nève, Jean, Michalski, Jean-Claude
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Glycobiology and Extracellular Matrices
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871502/
https://ncbi.nlm.nih.gov/pubmed/20332087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.089748
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