Subnuclear Proteomics in Colorectal Cancer: IDENTIFICATION OF PROTEINS ENRICHED IN THE NUCLEAR MATRIX FRACTION AND REGULATION IN ADENOMA TO CARCINOMA PROGRESSION

Abnormalities in nuclear phenotype and chromosome structure are key features of cancer cells. Investigation of the protein determinants of nuclear subfractions in cancer may yield molecular insights into aberrant chromosome function and chromatin organization and in addition may yield biomarkers for...

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Autori principali: Albrethsen, Jakob, Knol, Jaco C., Piersma, Sander R., Pham, Thang V., de Wit, Meike, Mongera, Sandra, Carvalho, Beatriz, Verheul, Henk M. W., Fijneman, Remond J. A., Meijer, Gerrit A., Jimenez, Connie R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2010
Soggetti:
Translational Applications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871429/
https://ncbi.nlm.nih.gov/pubmed/20089989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M900546-MCP200
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