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An oligomer complementary to c-myb-encoded mRNA inhibits proliferation of human myeloid leukemia cell lines.

To study the role of the protooncogene c-myb in regulating myeloid leukemia cell proliferation and differentiation, we exposed cells of the human leukemia lines HL-60, ML-3, KG-1, and KG-1a to an oligodeoxynucleotide complementary to an 18-base-pair (bp) sequence of c-myb-encoded mRNA. This treatmen...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Anfossi, G, Gewirtz, A M, Calabretta, B
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287136/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2541445/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.9.3379
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