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Heat shock causes a decrease in polysomes and appearance of stress granules in trypanosomes independently of eIF2α phosphorylation at threonine 169, the residue equivalent to serine 51 in mammalian eIF2α
In trypanosomes there is an almost total reliance on post-transcriptional mechanisms to alter gene expression and here heat shock was used to investigate the response to an environmental signal. Heat shock rapidly and reversibly induced a decrease in polysome abundance and the consequent changes in...
Gorde:
| Egile Nagusiak: | , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2008
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2871294/ https://ncbi.nlm.nih.gov/pubmed/18713834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.031823 |
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