Identification and characterization of a membrane-bound cytotoxin of murine cytolytic lymphocytes that is related to tumor necrosis factor/cachectin.

Cytotoxic T lymphocytes (CTLs) kill their targets by a contact-dependent mechanism. We investigated the possibility that the CTL membranes themselves could exert direct cytotoxic activity. Murine CTLs that had been fixed with paraformaldehyde retained a slow cytotoxic activity toward various target...

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Bibliografiska uppgifter
Huvudupphovsmän: Liu, C C, Detmers, P A, Jiang, S B, Young, J D
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1989
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC287116/
https://ncbi.nlm.nih.gov/pubmed/2654942
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