Rationally designed pharmacogenomic treatment using concurrent capecitabine and radiotherapy for glioblastoma; gene expression profiles associated with outcome

PURPOSE: Previous preclinical studies suggested that concurrent capecitabine and radiation could be an effective new treatment modality for glioblastoma (GBM). In the current study we investigate toxicity and response to this regimen and explore associations between gene expression and patient outco...

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Hauptverfasser: Grunda, Jessica M., Fiveash, John, Palmer, Cheryl A., Cantor, Alan, Fathallah-Shaykh, Hassan M., Nabors, L. Burt, Johnson, Martin R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871063/
https://ncbi.nlm.nih.gov/pubmed/20460474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-3151
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