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The Yeast PUF Protein Puf5 Has Pop2-Independent Roles in Response to DNA Replication Stress

PUFs are RNA binding proteins that promote mRNA deadenylation and decay and inhibit translation. Yeast Puf5 is the prototype for studying PUF-dependent gene repression. Puf5 binds to the Pop2 subunit of the Ccr4-Pop2-NOT mRNA deadenylase, recruiting the deadenylase and associated translational repre...

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Bibliographic Details
Main Authors: Traven, Ana, Lo, Tricia L., Lithgow, Trevor, Heierhorst, Jörg
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871046/
https://ncbi.nlm.nih.gov/pubmed/20498834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010651
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