Tyrosine phosphorylation of the insulin receptor is not required for receptor internalization: studies in 2,4-dinitrophenol-treated cells.

The relation between insulin-stimulated autophosphorylation of the insulin receptor and internalization of the receptor was studied in Fao rat hepatoma cells. Treatment of Fao cells with 2,4-dinitrophenol for 45 min depleted cellular ATP by 80% and equally inhibited insulin-stimulated receptor autop...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Backer, J M, Kahn, C R, White, M F
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1989
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287096/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2470095/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.9.3209
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