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FoxL2 Is Required for Activin Induction of the Mouse and Human Follicle-Stimulating Hormone β-Subunit Genes

Activin is a major physiological regulator of FSH. We identify FoxL2 as a critical component in activin induction of FSHβ, both for the mouse gene, induction of which is Sma- and Mad-related protein (Smad) dependent, and for the human gene that is Smad independent. FoxL2 has been shown to regulate g...

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Autors principals: Corpuz, Patrick S., Lindaman, Lacey L., Mellon, Pamela L., Coss, Djurdjica
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2870942/
https://ncbi.nlm.nih.gov/pubmed/20233786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0425
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