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Runt-Related Transcription Factors Impair Activin Induction of the Follicle-Stimulating Hormone β-Subunit Gene

Synthesis of the FSH β-subunit (FSHβ) is critical for normal reproduction in mammals, and its expression within the pituitary gonadotrope is tightly regulated by activin. Here we show that Runt-related (RUNX) proteins, transcriptional regulators known to interact with TGFβ signaling pathways, suppre...

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Detalhes bibliográficos
Main Authors: Breen, Kellie M., Thackray, Varykina G., Coss, Djurdjica, Mellon, Pamela L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875819/
https://ncbi.nlm.nih.gov/pubmed/20357224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-0949
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