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Unstable Hoogsteen base pairs adjacent to echinomycin binding sites within a DNA duplex.

The bisintercalation complex present between the DNA octamer [d(ACGTACGT)]2 and the cyclic octadepsipeptide antibiotic echinomycin has been studied by one- and two-dimensional proton NMR, and the results obtained have been compared with the crystal structures of related DNA-echinomycin complexes. Tw...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Gilbert, D E, van der Marel, G A, van Boom, J H, Feigon, J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287053/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2717609/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.9.3006
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