Unstable Hoogsteen base pairs adjacent to echinomycin binding sites within a DNA duplex.
The bisintercalation complex present between the DNA octamer [d(ACGTACGT)]2 and the cyclic octadepsipeptide antibiotic echinomycin has been studied by one- and two-dimensional proton NMR, and the results obtained have been compared with the crystal structures of related DNA-echinomycin complexes. Tw...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287053/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2717609/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.9.3006 |
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