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cAMP and forskolin decrease gamma-aminobutyric acid-gated chloride flux in rat brain synaptoneurosomes.

The effects of the cyclic nucleotide cAMP on gamma-aminobutyric acid-gated chloride channel function were investigated. The membrane-permeant cAMP analog N6,O2'-dibutyryladenosine 3',5'-cyclic monophosphate inhibited muscimol-induced 36Cl- uptake into rat cerebral cortical synaptoneur...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Heuschneider, G, Schwartz, R D
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287035/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2468163/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.8.2938
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