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Synthesis of germ-line gamma 1 immunoglobulin heavy-chain transcripts in resting B cells: induction by interleukin 4 and inhibition by interferon gamma.

Interleukin 4 (IL-4) induces the expression of IgG1 and IgE in lipopolysaccharide-stimulated B cells. Previous studies have suggested that heavy-chain class switching may be regulated by increasing the accessibility of specific switch regions to switch recombinases. In this study, we have used an RN...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Berton, M T, Uhr, J W, Vitetta, E S
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1989
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287012/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2495537/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.8.2829
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