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Amino-acid change on the antigenic region B1 of H3 haemagglutinin may be a trigger for the emergence of drift strain of influenza A virus.

Sera from 27 children and eight older persons, which had been collected in 1998 and 1999 and showed haemagglutination-inhibition (HI) activity against influenza A/Sydney/5/97 (H3N2) strain, were characterized with a binding assay using chimeric haemagglutinin (HA) proteins between A/Aichi/2/68 (A/AI...

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Bibliographic Details
Main Authors: Sato, K., Morishita, T., Nobusawa, E., Tonegawa, K., Sakae, K., Nakajima, S., Nakajima, K.
Format: Artigo
Language:Inglês
Published: Cambridge University Press 2004
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2870118/
https://ncbi.nlm.nih.gov/pubmed/15188708
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