A Novel Point Mutation in Helix 10 of the Human Glucocorticoid Receptor Causes Generalized Glucocorticoid Resistance by Disrupting the Structure of the Ligand-Binding Domain

Lignende værker

• Structural Analysis on the Pathologic Mutant Glucocorticoid Receptor Ligand-Binding Domains
  af: Hurt, Darrell E., et al.
  Udgivet: (2016)
• Noncoding RNA Gas5 Is a Growth Arrest and Starvation-Associated Repressor of the Glucocorticoid Receptor
  af: Kino, Tomoshige, et al.
  Udgivet: (2010)
• A Novel Point Mutation in the DNA-Binding Domain (DBD) of the Human Glucocorticoid Receptor Causes Primary Generalized Glucocorticoid Resistance by Disrupting the Hydrophobic Structure of its DBD
  af: Roberts, Michael L., et al.
  Udgivet: (2013)
• Circadian rhythm transcription factor CLOCK regulates the transcriptional activity of the glucocorticoid receptor by acetylating its hinge region lysine cluster: potential physiological implications
  af: Nader, Nancy, et al.
  Udgivet: (2009)
• A Novel Point Mutation of the Human Glucocorticoid Receptor Gene Causes Primary Generalized Glucocorticoid Resistance Through Impaired Interaction With the LXXLL Motif of the p160 Coactivators: Dissociation of the Transactivating and Transreppressive Activities
  af: Nicolaides, Nicolas C., et al.
  Udgivet: (2014)