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ITAM-mediated Signaling by the T-Cell Antigen Receptor
Signal transduction by the T-cell antigen receptor (TCR) is initiated by phosphorylation of conserved motifs (ITAMs) contained within the cytoplasmic domains of the invariant subunits. TCR complexes contain a total of 10 ITAMs and this unusual configuration has prompted studies of the role of specif...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2869518/ https://ncbi.nlm.nih.gov/pubmed/20516133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a002485 |
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