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ITAM-mediated Signaling by the T-Cell Antigen Receptor

Signal transduction by the T-cell antigen receptor (TCR) is initiated by phosphorylation of conserved motifs (ITAMs) contained within the cytoplasmic domains of the invariant subunits. TCR complexes contain a total of 10 ITAMs and this unusual configuration has prompted studies of the role of specif...

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Bibliografiske detaljer
Main Authors: Love, Paul E., Hayes, Sandra M.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869518/
https://ncbi.nlm.nih.gov/pubmed/20516133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a002485
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