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Dietary Choline Reverses Some, but Not All, Effects of Folate Deficiency on Neurogenesis and Apoptosis in Fetal Mouse Brain

In mice, maternal dietary folate, a cofactor in 1-carbon metabolism, modulates neurogenesis and apoptosis in the fetal brain. Similarly, maternal dietary choline, an important methyl-donor, also influences these processes. Choline and folate are metabolically interrelated, and we determined whether...

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Bibliografiske detaljer
Main Authors: Craciunescu, Corneliu N., Johnson, Amy R., Zeisel, Steven H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Nutrition 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869500/
https://ncbi.nlm.nih.gov/pubmed/20392884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.110.122044
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