Caffeine and 2-Aminoethoxydiphenyl Borate (2-APB) Have Different Ability to Inhibit Intracellular Calcium Mobilization in Pancreatic Acinar Cell

Inositol 1,4,5-trisphosphate receptors (InsP(3)Rs) modulate Ca(2+) release from intracellular Ca(2+) store and are extensively expressed in the membrane of endoplasmic/sarcoplasmic reticulum and Golgi. Although caffeine and 2-aminoethoxydiphenyl borate (2-APB) have been widely used to block InsP(3)R...

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Autores principales: Choi, Kyung Jin, Kim, Kab Sung, Kim, Se Hoon, Kim, Dong Kwan, Park, Hyung Seo
Formato: Artigo
Lenguaje:Inglês
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2010
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869459/
https://ncbi.nlm.nih.gov/pubmed/20473382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2010.14.2.105
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