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CRAC channel gating and its modulation by STIM1 and 2‐aminoethoxydiphenyl borate
Ca(2+) release‐activated Ca(2+) (CRAC) channels play an essential role in the immune system. The pore‐forming subunit, Orai1, is an important pharmacological target. Here, we summarize the recent discoveries on the structure–function relationship of Orai1, as well as its interaction with the native...
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| Veröffentlicht in: | J Physiol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5430206/ https://ncbi.nlm.nih.gov/pubmed/27753099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273130 |
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