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Voltage-gated sodium channels are required for heart development in zebrafish

RATIONALE: Voltage-gated sodium channels initiate action potentials in excitable tissues. Mice in which Scn5A (the predominant sodium channel gene in heart) has been knocked out die early in development with cardiac malformations by mechanisms which have yet to be determined. OBJECTIVE: Here we addr...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Chopra, Sameer S., Stroud, Dina Myers, Watanabe, Hiroshi, Bennett, Jeffrey S., Burns, C. Geoffrey, Wells, K. Sam, Yang, Tao, Zhong, Tao P., Roden, Dan M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869449/
https://ncbi.nlm.nih.gov/pubmed/20339120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.213132
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