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Long-Term Ritonavir Exposure Increases Fatty Acid and Glycerol Recycling in 3T3-L1 Adipocytes as Compensatory Mechanisms for Increased Triacylglycerol Hydrolysis

Lipodystrophy with high nonesterified fatty acid (FA) efflux is reported in humans receiving highly active antiretroviral therapy (HAART) to treat HIV infection. Ritonavir, a common component of HAART, alters adipocyte FA efflux, but the mechanism for this effect is not established. To investigate r...

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Detalhes bibliográficos
Main Authors: Adler-Wailes, Diane C., Guiney, Evan L., Wolins, Nathan E., Yanovski, Jack A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869264/
https://ncbi.nlm.nih.gov/pubmed/20228169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-1364
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