LYN is a mediator of epithelial-mesenchymal transition and target of dasatinib in breast cancer

Epithelial-mesenchymal transition (EMT), a switch of polarized epithelial cells to a migratory, fibroblastoid phenotype, is considered a key process driving tumor cell invasiveness and metastasis. Using breast cancer cell lines as a model system, we sought to discover gene-expression signatures of E...

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Bibliografiske detaljer
Main Authors: Choi, Yoon-La, Bocanegra, Melanie, Kwon, Mi Jeong, Shin, Young Kee, Nam, Seok Jin, Yang, Jung-Hyun, Kao, Jessica, Godwin, Andrew K., Pollack, Jonathan R.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869247/
https://ncbi.nlm.nih.gov/pubmed/20215510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3141
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