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Mutations in the KRAS2 oncogene during progressive stages of human colon carcinoma.

A series of colon carcinomas, adenomas, and adjacent tissues were analyzed for ploidy alterations and mutations in KRAS2. To increase the sensitivity for identifying mutations, we used histological enrichment, cell sorting, and DNA amplification by the polymerase-catalyzed chain reaction followed by...

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Detalles Bibliográficos
Autores principales: Burmer, G C, Loeb, L A
Formato: Artigo
Lenguaje:Inglês
Publicado: 1989
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC286921/
https://ncbi.nlm.nih.gov/pubmed/2648401
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