Isotype switching by a microinjected mu immunoglobulin heavy chain gene in transgenic mice.
Immunization of transgenic mice carrying an immunoglobulin mu heavy chain resulted in a response dominated by expression of the transgene variable region. Unexpectedly, in a large proportion of the antibody produced by immunized mice, the transgene variable region was associated with IgG rather than...
שמור ב:
| הוצא לאור ב: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
1989
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286909/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2494666/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.7.2346 |
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