Isotype switching by a microinjected mu immunoglobulin heavy chain gene in transgenic mice.

Immunization of transgenic mice carrying an immunoglobulin mu heavy chain resulted in a response dominated by expression of the transgene variable region. Unexpectedly, in a large proportion of the antibody produced by immunized mice, the transgene variable region was associated with IgG rather than...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Durdik, J, Gerstein, R M, Rath, S, Robbins, P F, Nisonoff, A, Selsing, E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286909/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2494666/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.7.2346
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