Isotype switching by a microinjected mu immunoglobulin heavy chain gene in transgenic mice.

Immunization of transgenic mice carrying an immunoglobulin mu heavy chain resulted in a response dominated by expression of the transgene variable region. Unexpectedly, in a large proportion of the antibody produced by immunized mice, the transgene variable region was associated with IgG rather than...

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Библиографические подробности
Главные авторы: Durdik, J, Gerstein, R M, Rath, S, Robbins, P F, Nisonoff, A, Selsing, E
Формат: Artigo
Язык:Inglês
Опубликовано: 1989
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC286909/
https://ncbi.nlm.nih.gov/pubmed/2494666
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