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Gene Expression and Genetic Variation in Response to Endoplasmic Reticulum Stress in Human Cells

The accumulation of unfolded or misfolded proteins in the endoplasmic reticulum (ER) results in the condition called “ER stress,” which induces the unfolded protein response (UPR), a complex cellular process that includes changes in expression of many genes. Failure to restore homeostasis in the ER...

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Detalhes bibliográficos
Main Authors: Dombroski, Beth A., Nayak, Renuka R., Ewens, Kathryn G., Ankener, Wendy, Cheung, Vivian G., Spielman, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869002/
https://ncbi.nlm.nih.gov/pubmed/20398888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2010.03.017
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