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Effects of the NUP98-DDX10 oncogene on primary human CD34+ cells: Role of a conserved helicase motif
NUP98 gene rearrangements occur in acute myeloid leukemia and result in the expression of fusion proteins. One of the most frequent is NUP98-DDX10 that fuses a portion of NUP98 to a portion of DDX10, a putative DEAD-box RNA helicase. Here we show that NUP98-DDX10 dramatically increases proliferation...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2868946/ https://ncbi.nlm.nih.gov/pubmed/20339440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2010.42 |
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