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Investigating the Epigenetic Effects of a Prototype Smoke-Derived Carcinogen in Human Cells
Global loss of DNA methylation and locus/gene-specific gain of DNA methylation are two distinct hallmarks of carcinogenesis. Aberrant DNA methylation is implicated in smoking-related lung cancer. In this study, we have comprehensively investigated the modulation of DNA methylation consequent to chro...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2868871/ https://ncbi.nlm.nih.gov/pubmed/20485678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010594 |
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