UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis

Polycomb (PcG) and Trithorax (TrxG) group proteins act antagonistically to establish tissue-specific patterns of gene expression. The PcG protein Ezh2 facilitates repression by catalysing histone H3-Lys27 trimethylation (H3K27me3). For expression, H3K27me3 marks are removed and replaced by TrxG prot...

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Bibliographische Detailangaben
Hauptverfasser: Seenundun, Shayesta, Rampalli, Shravanti, Liu, Qi-Cai, Aziz, Arif, Palii, Carmen, Hong, SunHwa, Blais, Alexandre, Brand, Marjorie, Ge, Kai, Dilworth, Francis Jeffrey
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868576/
https://ncbi.nlm.nih.gov/pubmed/20300060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.37
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