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Functional Redundancy of R7 RGS Proteins in ON-Bipolar Cell Dendrites

PURPOSE. In the Gβ5(−/−) mouse, the electroretinogram (ERG) b-wave is absent, and the R7 subfamily of regulators of G protein signaling (RGS), which includes RGS6, -7, -9, and -11, is downregulated. Mutant mouse strains deficient in RGS7 or -11 were characterized, and the SG711 strain which is defic...

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Autors principals: Chen, Frank S., Shim, Hoon, Morhardt, Duncan, Dallman, Rebecca, Krahn, Elizabeth, McWhinney, Ludine, Rao, Anjali, Gold, Stephen J., Chen, Ching-Kang
Format: Artigo
Idioma:Inglês
Publicat: Association for Research in Vision and Ophthalmology, Inc. 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868441/
https://ncbi.nlm.nih.gov/pubmed/19797210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4084
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