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Inhibition of Retinal Detachment-Induced Apoptosis in Photoreceptors by a Small Peptide Inhibitor of the Fas Receptor

PURPOSE. To test the effect of a small peptide inhibitor (Met12) of the Fas receptor on the activation of extrinsic and intrinsic apoptosis pathways after retinal detachment. METHODS. Retinal-RPE separation was created in Brown Norway rats by subretinal injection of 1% hyaluronic acid. Met12, derive...

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Autori principali: Besirli, Cagri G., Chinskey, Nicholas D., Zheng, Qiong-Duan, Zacks, David N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Association for Research in Vision and Ophthalmology, Inc. 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868404/
https://ncbi.nlm.nih.gov/pubmed/19850829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4439
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