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Genomic disorders: A window into human gene and genome evolution

Gene duplications alter the genetic constitution of organisms and can be a driving force of molecular evolution in humans and the great apes. In this context, the study of genomic disorders has uncovered the essential role played by the genomic architecture, especially low copy repeats (LCRs) or seg...

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Detalhes bibliográficos
Main Authors: Carvalho, Claudia M. B., Zhang, Feng, Lupski, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868291/
https://ncbi.nlm.nih.gov/pubmed/20080665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906222107
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