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Structural variation of the human genome: mechanisms, assays, and role in male infertility

Genomic disorders are defined as diseases caused by rearrangements of the genome incited by a genomic architecture that conveys instability. Y-chromosome related dysfunctions such as male infertility are frequently associated with gross DNA rearrangements resulting from its peculiar genomic architec...

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Detalhes bibliográficos
Main Authors: Carvalho, Claudia M.B., Zhang, Feng, Lupski, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179416/
https://ncbi.nlm.nih.gov/pubmed/21210740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/19396368.2010.527427
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