Загрузка...
Genetic architecture of a complex trait and its implications for fitness and genome-wide association studies
A model is investigated in which mutations that affect a complex trait (e.g., heart disease) also affect fitness because the trait is a component of fitness or because the mutations have pleiotropic effects on fitness. The model predicts that the genetic variance, and hence the heritability, in the...
Сохранить в:
Главный автор: | |
---|---|
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
National Academy of Sciences
2010
|
Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2868283/ https://ncbi.nlm.nih.gov/pubmed/20133822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906182107 |
Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|