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Improving threading algorithms for remote homology modeling by combining fragment and template comparisons

In this work, we develop a method called FTCOM for assessing the global quality of protein structural models for targets of medium and hard difficulty (remote homology) produced by structure prediction approaches such as threading or ab initio structure prediction. FTCOM requires the C(α) coordinate...

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Autors principals: Zhou, Hongyi, Skolnick, Jeffrey
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868272/
https://ncbi.nlm.nih.gov/pubmed/20455261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22717
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