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Improving threading algorithms for remote homology modeling by combining fragment and template comparisons

In this work, we develop a method called FTCOM for assessing the global quality of protein structural models for targets of medium and hard difficulty (remote homology) produced by structure prediction approaches such as threading or ab initio structure prediction. FTCOM requires the C(α) coordinate...

詳細記述

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書誌詳細
主要な著者: Zhou, Hongyi, Skolnick, Jeffrey
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868272/
https://ncbi.nlm.nih.gov/pubmed/20455261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22717
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