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Structure of the catalytic domain of the human mitochondrial Lon protease: Proposed relation of oligomer formation and activity
ATP-dependent proteases are crucial for cellular homeostasis. By degrading short-lived regulatory proteins, they play an important role in the control of many cellular pathways and, through the degradation of abnormally misfolded proteins, protect the cell from a buildup of aggregates. Disruption or...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2868241/ https://ncbi.nlm.nih.gov/pubmed/20222013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.376 |
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