Structure of the catalytic domain of the human mitochondrial Lon protease: Proposed relation of oligomer formation and activity

ATP-dependent proteases are crucial for cellular homeostasis. By degrading short-lived regulatory proteins, they play an important role in the control of many cellular pathways and, through the degradation of abnormally misfolded proteins, protect the cell from a buildup of aggregates. Disruption or...

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Hauptverfasser: García-Nafría, Javier, Ondrovičová, Gabriela, Blagova, Elena, Levdikov, Vladimir M, Bauer, Jacob A, Suzuki, Carolyn K, Kutejová, Eva, Wilkinson, Anthony J, Wilson, Keith S
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley Subscription Services, Inc., A Wiley Company 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868241/
https://ncbi.nlm.nih.gov/pubmed/20222013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.376
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