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Model-based method for transcription factor target identification with limited data
We present a computational method for identifying potential targets of a transcription factor (TF) using wild-type gene expression time series data. For each putative target gene we fit a simple differential equation model of transcriptional regulation, and the model likelihood serves as a score to...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867914/ https://ncbi.nlm.nih.gov/pubmed/20385836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914285107 |
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