Comprehensive assessment of variation at the transforming growth factor β type 1 receptor locus and colorectal cancer predisposition

The role of transforming growth factor β receptor type 1 (TGFBR1) polymorphisms, particularly a coding CGC insertion (rs11466445, TGFBR1*6A/9A) in exon 1, has been extensively investigated in regard to colorectal cancer (CRC) risk. These investigations have generated conflicting results. More recent...

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Detalhes bibliográficos
Main Authors: Carvajal-Carmona, Luis G., Churchman, Mike, Bonilla, Carolina, Walther, Axel, Lefèvre, Jeremie H., Kerr, David, Dunlop, Malcolm, Houlston, Richard, Bodmer, Walter F., Tomlinson, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867909/
https://ncbi.nlm.nih.gov/pubmed/20368424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002816107
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