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Claudin-2–deficient mice are defective in the leaky and cation-selective paracellular permeability properties of renal proximal tubules
Claudin-2 is highly expressed in tight junctions of mouse renal proximal tubules, which possess a leaky epithelium whose unique permeability properties underlie their high rate of NaCl reabsorption. To investigate the role of claudin-2 in paracellular NaCl transport in this nephron segment, we gener...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867900/ https://ncbi.nlm.nih.gov/pubmed/20385797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912901107 |
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