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Drug target prediction and prioritization: using orthology to predict essentiality in parasite genomes

BACKGROUND: New drug targets are urgently needed for parasites of socio-economic importance. Genes that are essential for parasite survival are highly desirable targets, but information on these genes is lacking, as gene knockouts or knockdowns are difficult to perform in many species of parasites....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Doyle, Maria A, Gasser, Robin B, Woodcroft, Ben J, Hall, Ross S, Ralph, Stuart A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867826/
https://ncbi.nlm.nih.gov/pubmed/20361874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-222
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