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Benzo[a]pyrene diol epoxide suppresses retinoic acid receptor-β(2 )expression by recruiting DNA (cytosine-5-)-methyltransferase 3A

Tobacco smoke is an important risk factor for various human cancers, including esophageal cancer. How benzo [a]pyrene diol epoxide (BPDE), a carcinogen present in tobacco smoke as well as in environmental pollution, induces esophageal carcinogenesis has yet to be defined. In this study, we investiga...

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Detalhes bibliográficos
Main Authors: Ye, Fei, Xu, Xiao-Chun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867823/
https://ncbi.nlm.nih.gov/pubmed/20426865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-93
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