On the mechanism of action of ribonucleases: dinucleotide cleavage catalyzed by imidazole and Zn2+.
Cyclization/cleavage of the 2-(p-nitrophenyl) phosphate ester of propylene glycol is catalyzed by imidazole and, much more effectively, by Zn2+ with imidazole. In the latter case, the mechanism involves simultaneous Lewis acid/base catalysis. Similar Zn2+ and imidazole catalysis of cyclization/cleav...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286781/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2467290/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.6.1746 |
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